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About Us

Mitozz, Designed by Recognized Experts in Mitochondria Science

Founding scientists Dr. Guillermo Ceballos and Dr. Francisco Villarreal have published more than 68 peer-reviewed studies on (–)-epicatechin, building a substantial body of research related to mitochondrial renewal, muscle health, lipid metabolism, and vascular function.

Concept: The Pinnacle of Scientific Evidence

Beyond formulation—a legacy of over 68 peer-reviewed studies.

MITOZZ is not merely an (–)-epicatechin capsule. MITOZZ represents the product of an extensive body of research on mitochondrial renewal and vascular function, established by FMG Sciences founders Dr. Guillermo Ceballos and Dr. Francisco Villarreal through over 30 years of study and more than 68 peer-reviewed publications.

Established Mechanism of Action: At the Molecular Level

A 3-step cascade to optimize health from the vascular system to the cellular core.

Step 1: Vascular Endothelial Activation (The NO Pathway) By inhibiting the enzyme arginase, (–)-epicatechin maximizes the availability of L-arginine, facilitating the efficient production of Nitric Oxide (NO). This optimizes blood flow and ensures the delivery of oxygen and nutrients to tissues throughout the body.

Step 2: Mitochondrial Biogenesis (Cellular Reboot) NO signaling serves as a catalyst to activate key pathways such as PGC-1α. This process promotes the "renewal" of mitochondria, triggering biogenesis to restore cellular energy production at its source.

Step 3: Gene Expression & Tissue Maintenance Consistent intake influences gene expression profiles linked to follistatin (muscle repair) and AMPK (metabolic balance), effectively counteracting age-related declines in physical function.

Prospective Clinical insights: Bridging Nutraceuticals and Pharmaceuticals

Exploring the potential to support the three pillars of healthy aging: Muscle, Metabolism, and Vasculature.
  • Muscle Maintenance: Research suggests that (–)-epicatechin may be involved in the modulation of Follistatin (a myostatin antagonist). Current studies are exploring the potential role of this compound in supporting the natural maintenance of skeletal muscle mass and quality.
  • Metabolic Balance: Scientific interest focuses on how (–)-epicatechin interacts with the AMPK pathway, a key regulator of cellular energy. This research suggests a potential for the compound to assist in maintaining lipid metabolic balance and supporting overall systemic energy homeostasis.
  • Vascular Vitality: Studies have observed correlations between (–)-epicatechin intake and markers of eNOS activity. These findings indicate the possibility of (–)-epicatechin supporting healthy endothelial function through Nitric Oxide (NO) pathways, contributing to the maintenance of sound vascular health.

The Foundation of Trust: The FMG Sciences Team

Unprecedented transparency, led by the researchers.
  • Mani Agrawal, CEO: A strategic leader expert in translating cutting-edge scientific research into real-world health solutions.
  • Francisco Villarreal, MD, PhD (CMO): A world-renowned physician-scientist with 130+ publications. His pioneering work has redefined our understanding of mitochondrial and cardiovascular biology.
  • Guillermo Ceballos, MD, PhD (CSO): An accomplished researcher with 275+ publications. He leads the world in researching (–)-epicatechin’s role in metabolic balance and oxidative stress.

Mitochondrial Biogenesis and Aging

Muscle regeneration

Lipid metabolism

Vascular function

The Researchers Behind MITOZZ

Mani Agrawal, CEO

A leader experienced in translating scientific research into real-world solutions, with a background spanning MuZero and Dastur International, bridging innovation, strategy, and societal impact.

Francisco Villarreal,
Chief Medical Officer, MD, PhD | FMG Health Sciences, Inc.

A physician-scientist with more than 130 published research papers in cardiac and metabolic health. His work on (–)-epicatechin has contributed to a deeper understanding of mitochondrial and cardiovascular biology.

Guillermo Ceballos,
Chief Scientific Officer, MD, PhD | FMG Health Sciences, Inc.

An accomplished researcher with over 275 peer-reviewed publications, focusing on (–)-epicatechin in relation to metabolic balance and oxidative stress.